PRESENTATION

Building biochips for rapid diagnosis of severe infections

Photonic and plasmonic sensing may collectively address unmet medical diagnostic needs when implemented in the context of integrated optics. On one side, Photonic integrated circuits (PIC) technology allows the integration of multiple optical components onto the same substrate, enabling fast measurement, multi-functionality, miniaturization, and scalability. On the other side, plasmonic sensors can boost the specifications of diagnostic solutions like sensitivity (strong light-analyte interaction) and small sample volume requirements (ultra-small sensing area). Bringing the best of those worlds onto a CMOS- compatible PIC platform can meet those goals while offering lower production cost and high-volume manufacturing of disposable chips. We will present Bialoom’s unique silicon-plasmophotonic biosensing technology that enables monolithic co-integration of CMOS-compatible Mach Zehnder interferometers with plasmonic transducers into robust, stable and flexible biosensor PICs. We will review the capabilities of this technology and we will present the progress towards the development of a powerful plasmo-photonic diagnostic biochip towards immediate diagnosis of acute infections.